30–100 kHz, 2 ns passively Q‐switched laser for fast and efficient photoacoustic microscopy

Author:

He Hongsen12ORCID,Wang Hanjie1,You Huiyue1,Dong Xin3,Shi Jiawei3,Dong Jun12

Affiliation:

1. Laboratory of Laser and Applied Photonics (LLAP), Department of Electronic Engineering, School of Electronic Science and Engineering Xiamen University Xiamen China

2. Fujian Key Laboratory of Ultrafast Laser Technology and Applications Xiamen University Xiamen China

3. Department of Electrical and Electronic Engineering The University of Hong Kong Hong Kong China

Abstract

AbstractActively Q‐switched (AQS) fiber laser and solid‐state laser (SSL) are widely used for photoacoustic microscopy (PAM). In contrast, passively Q‐switched (PQS) SSL not only maintains most of the merits of AQS lasers, but also exhibits unique advantages, including the pulse width (PW), pulse repetition rate (PRR) tunability, wavelength, compactness, and cost. These advantages all benefit the PAM. However, there are few reports demonstrating the performance of PQS‐SSL on PA imaging. Here, we demonstrate a compact PQS‐SSL for fast and efficient PA imaging. The laser uniquely maintains a constant PW (~2 ns) and pulse energy (~3 μJ) during the PRR variation (30–100 kHz), which is valuable for preserving a stabilized imaging performance at different scanning rates. The PA imaging performance is compared by a resolution target and showcased by whole‐body scanning of an embryonic zebrafish in vivo. The performance indicates that PQS‐SSL is a promising candidate for PAM.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Xiamen Municipality

Program for New Century Excellent Talents in University

Publisher

Wiley

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