Light stimulation of mitochondria reduces blood glucose levels

Author:

Powner Michael B.1ORCID,Jeffery Glen2ORCID

Affiliation:

1. Department of Optometry and Visual Science, Centre for Applied Vision Research School of Health and Psychological Sciences, City, University of London London UK

2. Department of Visual Neuroscience, UCL Institute of Ophthalmology University College London London UK

Abstract

AbstractMitochondria regulate metabolism, but solar light influences its rate. Photobiomodulation (PBM) with red light (670 nm) increases mitochondrial membrane potentials and adenosine triphosphate production and may increase glucose demand. Here we show, with a glucose tolerance test, that PBM of normal subjects significantly reduces blood sugar levels. A 15 min exposure to 670 nm light reduced the degree of blood glucose elevation following glucose intake by 27.7%, integrated over 2 h after the glucose challenge. Maximum glucose spiking was reduced by 7.5%. Consequently, PBM with 670 nm light can be used to reduce blood glucose spikes following meals. This intervention may reduce damaging fluctuations of blood glucose on the body.

Funder

Sight Research UK

Publisher

Wiley

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