Combined anti‐PD‐1 and anti‐CTLA‐4 checkpoint blockade: Treatment of melanoma and immune mechanisms of action-Reference-Cited by-同舟云学术

Combined anti‐PD‐1 and anti‐CTLA‐4 checkpoint blockade: Treatment of melanoma and immune mechanisms of action

Published:2021-02-23 Issue:3 Volume:51 Page:544-556
ISSN:0014-2980
Container-title:European Journal of Immunology
language:en
Short-container-title:Eur. J. Immunol.

Author:

Willsmore Zena N.¹,Coumbe Ben G. T.¹,Crescioli Silvia¹,Reci Sara¹,Gupta Ayushi¹,Harris Robert J.¹,Chenoweth Alicia¹²,Chauhan Jitesh¹,Bax Heather J.¹³,McCraw Alexa¹,Cheung Anthony¹²,Osborn Gabriel¹,Hoffmann Ricarda M.¹,Nakamura Mano¹,Laddach Roman¹⁴,Geh Jenny L. C.⁵,MacKenzie‐Ross Alastair⁵,Healy Ciaran⁵,Tsoka Sophia⁴,Spicer James F.³,Josephs Debra H.¹³,Papa Sophie⁶⁷,Lacy Katie E.¹,Karagiannis Sophia N.¹²^ORCID

Affiliation:

1. St. John's Institute of Dermatology School of Basic & Medical Biosciences King's College London London SE1 9RT United Kingdom

2. Breast Cancer Now Research Unit School of Cancer & Pharmaceutical Sciences King's College London, Guy's Cancer Centre London United Kingdom

3. School of Cancer & Pharmaceutical Sciences King's College London London United Kingdom

4. Department of Informatics Faculty of Natural and Mathematical Sciences King's College London London United Kingdom

5. Department of Plastic Surgery at Guy's King's, and St. Thomas' Hospitals London United Kingdom

6. Department of Medical Oncology Guy's and St. Thomas' NHS Foundation Trust London United Kingdom

7. ImmunoEngineering School of Cancer and Pharmaceutical Sciences Faculty of Life Sciences and Medicine King's College London London United Kingdom

Funder

Medical Research Council

Breast Cancer Now

Cancer Research UK

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/eji.202048747

Reference93 articles.

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5. CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells.

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