Genetic dissection of a major haplotype associated with arthritis reveal FcγR2b and FcγR3 to act additively-Reference-Cited by-同舟云学术

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Genetic dissection of a major haplotype associated with arthritis reveal FcγR2b and FcγR3 to act additively

Published:2020-12-10 Issue:3 Volume:51 Page:682-693
ISSN:0014-2980
Container-title:European Journal of Immunology
language:en
Short-container-title:Eur. J. Immunol.

Author:

Vaartjes Daniëlle¹,Klaczkowska Dorota¹,Cragg Mark S²,Nandakumar Kutty Selva¹³,Bäckdahl Liselotte¹,Holmdahl Rikard¹³^ORCID

Affiliation:

1. Division of Medical Inflammation Research Department of Medical Biochemistry and Biophysics Karolinska Institute Stockholm Sweden

2. Antibody and Vaccine Group Centre for Cancer Immunology University of Southampton Faculty of Medicine Southampton UK

3. SMU‐KI United Medical Inflammation Center School of Pharmaceutical Sciences Southern Medical University Guangzhou China

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/eji.202048605

Reference39 articles.

1. Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes

2. Contribution of Human FcÎ³Rs to Disease with Evidence from Human Polymorphisms and Transgenic Animal Studies

3. Genetic control of collagen-induced arthritis in a cross with NOD and C57BL/10 mice is dependent on gene regions encoding complement factor 5 and FcγRIIb and is not associated with loci controlling diabetes

4. Genetically determined aberrant down-regulation of FcγRIIB1 in germinal center B cells associated with hyper-IgG and IgG autoantibodies in murine systemic lupus erythematosus

5. The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes

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1. Human MHC Class II and Invariant Chain Knock‐in Mice Mimic Rheumatoid Arthritis with Allele Restriction in Immune Response and Arthritis Association;Advanced Science;2024-04-11

2. Shift in perspective: autoimmunity protecting against rheumatoid arthritis;Annals of the Rheumatic Diseases;2024-02-27

3. Fcgr2b and Fcgr3 are the major genetic factors for cartilage antibody‐induced arthritis, overriding the effect of Hc encoding complement C5;European Journal of Immunology;2024-02-05

4. A subset of type-II collagen-binding antibodies prevents experimental arthritis by inhibiting FCGR3 signaling in neutrophils;Nature Communications;2023-09-23

5. Pathogenic antibody response to glucose-6-phosphate isomerase targets a modified epitope uniquely exposed on joint cartilage;Annals of the Rheumatic Diseases;2023-03-01

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