Damage‐inducible intragenic demethylation of the human TP53 tumor suppressor gene is associated with transcription from an alternative intronic promoter-Reference-Cited by-同舟云学术

Damage‐inducible intragenic demethylation of the human TP53 tumor suppressor gene is associated with transcription from an alternative intronic promoter

Published:2015-12-16 Issue:12 Volume:55 Page:1940-1951
ISSN:0899-1987
Container-title:Molecular Carcinogenesis
language:en
Short-container-title:Mol. Carcinog.

Author:

Blackburn James¹²,Roden Daniel L.³,Ng Robert¹²,Wu Jianmin⁴,Bosman Alexis⁵,Epstein Richard J.¹²⁶

Affiliation:

1. Laboratory of Genome EvolutionThe Kinghorn Cancer Centre, Garvan Institute for Medical ResearchSydneyAustralia

2. UNSW MedicineSt. Vincent's Clinical School, DarlinghurstSydneyAustralia

3. Laboratory of Cancer BiologyThe Kinghorn Cancer Centre, Garvan Institute for Medical ResearchSydneyAustralia

4. Laboratory of Cancer BioinformaticsThe Kinghorn Cancer Centre, Garvan Institute for Medical ResearchSydneyAustralia

5. Laboratory of Developmental and Stem Cell BiologyVictor Chang Cardiac Research InstituteSydneyAustralia

6. Clinical Informatics & Research CentreDepartment of OncologySt. Vincent's HospitalSydneyAustralia

Funder

Garvan Institute of Medical Research

Publisher

Wiley

Subject

Cancer Research,Molecular Biology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/mc.22441

Reference52 articles.

1. p53 Research: The Past Thirty Years and the Next Thirty Years

2. Epigenetic lesions causing genetic lesions in human cancer

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4. Methylation profile of TP53 regulatory pathway and mtDNA alterations in breast cancer patients lacking TP53 mutations

5. p53 alterations in human cancer: more questions than answers

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