Template‐Guided Silicon Micromotor Assembly for Enhanced Cell Manipulation

Author:

Gao Yuxin1,Ou Leyan1,Liu Kunfeng1,Guo Yuan2,Li Wanyuan1,Xiong Ze3,Wu Changjin4,Wang Jizhuang1,Tang Jinyao4,Li Dan1ORCID

Affiliation:

1. College of Chemistry and Materials Science Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications Jinan University Guangzhou, Guangdong 510632 P. R. China

2. The Third People's Hospital of Ganzhou Ganzhou City, Jiangxi Province 341000 P. R. China

3. Wireless and Smart Bioelectronics Lab School of Biomedical Engineering ShanghaiTech University Shanghai 201210 P. R. China

4. Department of Chemistry The University of Hong Kong Pokfulam Road Hong Kong P. R. China

Abstract

AbstractLight‐driven micro/nanorobots (LMNRs) are tiny, untethered machines with great potential in fields like precision medicine, nano manufacturing, and various other domains. However, their practicality hinges on developing light‐manipulation strategies that combine versatile functionalities, flexible design options, and precise controllability. Our study introduces an innovative approach to construct micro/nanorobots (MNRs) by utilizing micro/nanomotors as fundamental building blocks. Inspired by silicon Metal‐Insulator‐Semiconductor (MIS) solar cell principles, we design a new type of optomagnetic hybrid micromotors (OHMs). These OHMs have been skillfully optimized with integrated magnetic constituent, resulting in efficient light propulsion, precise magnetic navigation, and the potential for controlled assembly. One of the key features of the OHMs is their ability to exhibit diverse motion modes influenced by fracture surfaces and interactions with the environment, streamlining cargo conveyance along “micro expressway”—the predesigned microchannels. Further enhancing their versatility, a template‐guided assembly strategy facilitates the assembly of these micromotors into functional microrobots, encompassing various configurations such as “V‐shaped”, “N‐shaped”, and 3D structured microrobots. The heightened capabilities of these microrobots, underscore the innovative potential inherent in hybrid micromotor design and assembly, which provides a foundational platform for the realization of multi‐component microrobots. Our work moves a step toward forthcoming microrobotic entities boasting advanced functionalities.

Publisher

Wiley

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