Affiliation:
1. Leibniz Institute for Catalysis e.V. Albert-Einstein-Str. 29a 18059 Rostock Germany
2. Instituto de Estudios Ambientales y Recursos Naturales (i-UNAT) Universidad de Las Palmas de Gran Canaria (ULPGC), Campus de Tafira 35017 Las Palmas de Gran Canaria Spain
Abstract
AbstractDrawing inspiration from nature has long been a cornerstone of chemical innovation, with natural systems offering a wealth of untapped potential for discovery. In this minireview, we delve into the burgeoning field of cobaloxime catalysis in organic synthesis, which mimics the catalytic activity of the natural organometallic alkylcobalamine enzymes. Our focus lies on elucidating the latest advancements in this area, as well as delineating the primary mechanistic pathways at play. By describing, and comparing these mechanisms, we provide a comprehensive overview of the current state‐of‐the‐art, while also shedding light on the key unresolved challenges that await further exploration.
Funder
Deutsche Forschungsgemeinschaft