Phosphorothioate Modification of mRNA Accelerates the Rate of Translation Initiation to Provide More Efficient Protein Synthesis-Reference-Cited by-同舟云学术

Phosphorothioate Modification of mRNA Accelerates the Rate of Translation Initiation to Provide More Efficient Protein Synthesis

Published:2020-08-26 Issue:40 Volume:132 Page:17556-17560
ISSN:0044-8249
Container-title:Angewandte Chemie
language:en
Short-container-title:Angew. Chem.

Author:

Kawaguchi Daisuke¹,Kodama Ayumi¹,Abe Naoko¹²^ORCID,Takebuchi Kei¹,Hashiya Fumitaka²^ORCID,Tomoike Fumiaki²^ORCID,Nakamoto Kosuke¹^ORCID,Kimura Yasuaki¹^ORCID,Shimizu Yoshihiro³^ORCID,Abe Hiroshi¹²⁴⁵^ORCID

Affiliation:

1. Chemistry Department Nagoya University Furo-cho, Chikusa-ku Nagoya Aichi 464-8602 Japan

2. Research Center for Materials Science Nagoya University Furo-cho, Chikusa-ku Nagoya Aichi 464-8602 Japan

3. Biodynamics Research Center (BDR) RIKEN 6-2-3, Furuedai Suita Osaka 565-0874 Japan

4. CREST (Japan) Science and Technology Agency 7, Gobancho, Chiyoda-ku Tokyo 102-0076 Japan

5. Institute for Glyco-core Research Tokai National Higher Education and Research System Furo-cho, Chikusa-ku Nagoya Aichi 464-8601 Japan

Funder

Japan Science and Technology Agency

Japan Society for the Promotion of Science

Publisher

Wiley

Subject

General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ange.202007111

Reference45 articles.

2. Delivering the Messenger: Advances in Technologies for Therapeutic mRNA Delivery

3. mRNA vaccines — a new era in vaccinology

4. mRNA-Based Protein Replacement Therapy for the Heart

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