Affiliation:
1. Department of Applied Chemistry National Yang Ming Chiao Tung University (NYCU) Hsinchu 30010 Taiwan
2. Organization for Research Promotion Osaka Metropolitan University (OMU) 599-8531 Sakai Osaka Japan
Abstract
AbstractWe report a protocol for alkene hydroxyalkenylation. Using a persulfate anion as a one‐electron‐oxidation reagent and 1,2‐bis(phenylsulfonyl)ethylene as a radical acceptor in the presence of water, alkenes were converted into the corresponding 1‐phenylsulfonyl‐4‐hydroxyalkenes in good to high yields. The hydroxyalkenylation process involves the nucleophilic hydroxylation of alkene radical cations to give β‐hydroxyalkyl radicals, which, after a radical addition/β‐elimination sequence, provide the products. We also report a photocatalytic protocol for alkoxyalkenylation.
Funder
National Science and Technology Council