Rechargeable Afterglow Nanotorches for In Vivo Tracing of Cell‐Based Microrobots

Author:

Ma Gongcheng12,Dirak Musa3,Liu Zhongke1,Jiang Daoyong14,Wang Yue15,Xiang Chunbai1,Zhang Yuding1,Luo Yuan1,Gong Ping12,Cai Lintao12ORCID,Kolemen Safacan3,Zhang Pengfei12

Affiliation:

1. Guangdong Key Laboratory of Nanomedicine CAS-HK Joint Lab of Biomaterials CAS Key Laboratory of Biomedical Imaging Science and System Shenzhen Engineering Laboratory of Nanomedicine and Nanoformulations CAS Key Lab for Health Informatics Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 P. R. China

2. University of Chinese Academy of Sciences Beijing 100049 P.R. China

3. Department of Chemistry Koç University 34450 Istanbul Turkey

4. Postdoctoral lnnovation Practice Base Shenzhen Polytechnic University Shenzhen 518055 China

5. Cancer Centre Institute of Translational Medicine Faculty of Health Sciences University of Macau, Taipa Macau 999078 China

Abstract

AbstractAs one of the self‐luminescence imaging approaches that require pre‐illumination instead of real‐time light excitation, afterglow luminescence imaging has attracted increasing enthusiasm to circumvent tissue autofluorescence. In this work, we developed organic afterglow luminescent nanoprobe (nanotorch), which could emit persistent luminescence more than 10 days upon single light excitation. More importantly, the nanotorch could be remote charged by 660 nm light in a non‐invasive manner, which showed great potential for real‐time tracing the location of macrophage cell‐based microrobots.

Publisher

Wiley

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