Genome Mining Enabled by Biosynthetic Characterization Uncovers a Class of Benzoxazolinate‐Containing Natural Products in Diverse Bacteria-Reference-Cited by-同舟云学术

Genome Mining Enabled by Biosynthetic Characterization Uncovers a Class of Benzoxazolinate‐Containing Natural Products in Diverse Bacteria

Published:2022-11-17 Issue:51 Volume:134 Page:
ISSN:0044-8249
Container-title:Angewandte Chemie
language:en
Short-container-title:Angewandte Chemie

Author:

Shi Yi‐Ming¹²^ORCID,Crames Jan J.¹²,Czech Laura³,Bozhüyük Kenan A. J.¹²,Shi Yan‐Ni¹²,Hirschmann Merle²,Lamberth Stefanie²,Claus Peter⁴,Paczia Nicole⁴,Rückert Christian⁵,Kalinowski Jörn⁵,Bange Gert³,Bode Helge B.¹²⁶⁷^ORCID

Affiliation:

1. Department of Natural Products in Organismic Interactions Max Planck Institute for Terrestrial Microbiology 35043 Marburg Germany

2. Molecular Biotechnology Department of Biosciences Goethe University Frankfurt 60438 Frankfurt am Main Germany

3. Center for Synthetic Microbiology (SYNMIKRO) & Faculty of Chemistry Philipps University of Marburg 35043 Marburg Germany

4. Core Facility for Metabolomics and Small Molecule Mass Spectrometry Max Planck Institute for Terrestrial Microbiology 35043 Marburg Germany

5. Microbial Genomics and Biotechnology Center for Biotechnology (CeBiTec) Bielefeld University 33615 Bielefeld Germany

6. Senckenberg Gesellschaft für Naturforschung 60325 Frankfurt am Main Germany

7. Chemical Biology Department of Chemistry Philipps University of Marburg 35043 Marburg Germany

Funder

Alexander von Humboldt-Stiftung

HORIZON EUROPE European Research Council

Publisher

Wiley

Subject

General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ange.202206106

Reference40 articles.

1. Structure of an aromatization product of C-1027 chromophore

2. A new macromolecular antitumor antibiotic, C-1027. I. Discovery, taxonomy of producing organism, fermentation and biological activity.

3. Genes for Production of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus Are Clustered with the cagA Gene That Encodes the C-1027 Apoprotein

4. The Benzoxazolinate of C-1027 Confers Intercalative DNA Binding

5. C1027 Chromophore, a Potent New Enediyne Antitumor Antibiotic, Induces Sequence-Specific Double-Strand DNA Cleavage

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Metal-Organic Framework Derived Phytate-Iron for Efficient Synthesis of 2-Arylbenzoxazole via Hydrogen Transfer Strategy;Chinese Journal of Organic Chemistry;2023