Mechanochemical Iron‐Catalyzed Nitrene Transfer Reactions: Direct Synthesis of <i>N</i>‐Acyl Sulfonimidamides from Sulfinamides and Dioxazolones-Reference-Cited by-同舟云学术

Mechanochemical Iron‐Catalyzed Nitrene Transfer Reactions: Direct Synthesis of N‐Acyl Sulfonimidamides from Sulfinamides and Dioxazolones

Published:2023-12-21 Issue:5 Volume:136 Page:
ISSN:0044-8249
Container-title:Angewandte Chemie
language:en
Short-container-title:Angewandte Chemie

Author:

Pan Shulei¹,Mulks Florian F.¹,Wu Peng¹,Rissanen Kari²,Bolm Carsten¹^ORCID

Affiliation:

1. Institute of Organic Chemistry RWTH Aachen University Landoltweg 1 52074 Aachen Germany

2. University of Jyvaskyla Department of Chemistry P.O. Box. 35, Survontie 9 B 40014 Jyväskylä Finland

Abstract

AbstractA mechanochemical synthesis of sulfonimidamides by iron(II)‐catalyzed exogenous ligand‐free N‐acyl nitrene transfer to sulfinamides is reported. The one‐step method tolerates a wide range of sulfinamides with various substituents under solvent‐free ambient conditions. Compared to its solution‐phase counterpart, this mechanochemical approach shows better conversion and chemoselectivity. Mechanistic investigations by ESI‐MS revealed the generation of crucial nitrene iron intermediates.

Funder

China Scholarship Council

Fonds der Chemischen Industrie

Alexander von Humboldt-Stiftung

Publisher

Wiley

Subject

General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ange.202316702

Reference92 articles.

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