Alteration of the Catalytic Reaction Trajectory of a Vicinal Oxygen Chelate Enzyme by Directed Evolution-Reference-Cited by-同舟云学术

Alteration of the Catalytic Reaction Trajectory of a Vicinal Oxygen Chelate Enzyme by Directed Evolution

Published:2022-04-27 Issue:26 Volume:134 Page:
ISSN:0044-8249
Container-title:Angewandte Chemie
language:en
Short-container-title:Angewandte Chemie

Author:

Wang Yi Shuang¹,Zheng Wan²,Jiang Nan³,Jin Yun Xia¹,Meng Zi Kang¹,Sun Meng Xin²,Zong Yu Liang²,Xu Tong³,Zhu Jiapeng²,Tan Ren Xiang¹⁴^ORCID

Affiliation:

1. State Key Laboratory Cultivation Base for TCM Quality and Efficacy Nanjing University of Chinese Medicine Nanjing 210023 China

2. School of Medicine and Holistic Integrative Medicine Nanjing University of Chinese Medicine Nanjing 210023 China

3. Key Laboratory of Cardiovascular & Cerebrovascular Medicine School of Pharmacy Nanjing Medical University Nanjing 210023 China

4. State Key Laboratory of Pharmaceutical Biotechnology Institute of Functional Biomolecules School of Life Sciences Nanjing University Nanjing 210023 China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ange.202201321

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1. Crystal structures of alkylperoxo and anhydride intermediates in an intradiol ring-cleaving dioxygenase

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3. Studies of a Ring-Cleaving Dioxygenase Illuminate the Role of Cholesterol Metabolism in the Pathogenesis of Mycobacterium tuberculosis

4. Fosfomycin Resistance Protein (FosA) Is a Manganese Metalloglutathione Transferase Related to Glyoxalase I and the Extradiol Dioxygenases

5. New dioxygenase from metagenomic library from Brazilian soil: insights into antibiotic resistance and bioremediation