Rational Design of a Two‐Photon Fluorescent Probe for Human Cytochrome P450 3A and the Visualization of Mechanism‐Based Inactivation

Author:

Ning Jing12,Tian Zhenhao3,Wang Jiayue24,Wang Bo5,Tian Xiangge2,Yu Zhenlong2,Huo Xiaokui2,Feng Lei16,Cui Jingnan7,James Tony D.68,Ma Xiaochi12ORCID

Affiliation:

1. Second Affiliated Hospital of Dalian Medical University Dalian 116023 China

2. College of Integrative Medicine College of Pharmacy Dalian Medical University Dalian 116044 China

3. School of Life Sciences Northwestern Polytechnical University Xi'an 710072 China

4. Department of Pharmacy Peking University Shenzhen Hospital Shenzhen 518036 China

5. School of Medicine & Holistic Integrative Medicine Nanjing University of Chinese Medicine Nanjing China

6. School of Chemistry and Chemical Engineering Henan Normal University Xinxiang 453007 China

7. State Key Laboratory of Fine Chemicals Dalian University of Technology Dalian 116024 China

8. Department of Chemistry University of Bath Bath BA2 7AY United Kingdom

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

General Medicine

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