Asymmetric Synthesis of 2,2‐Difluorotetrahydrofurans through Palladium‐Catalyzed Formal [3+2] Cycloaddition-Reference-Cited by-同舟云学术

Asymmetric Synthesis of 2,2‐Difluorotetrahydrofurans through Palladium‐Catalyzed Formal [3+2] Cycloaddition

Published:2021-10 Issue:44 Volume:133 Page:23833-23837
ISSN:0044-8249
Container-title:Angewandte Chemie
language:en
Short-container-title:Angew. Chem.

Author:

Liu Jun¹,Yu Longhui¹,Zheng Changwu²,Zhao Gang¹^ORCID

Affiliation:

1. Key Laboratory of Synthetic Chemistry of Natural Substances Shanghai Institute of Organic Chemistry Chinese Academy of Sciences 345 Lingling Road Shanghai 200032 P.R. China

2. School of Pharmacy Shanghai University of Traditional Chinese Medicine 1200 Cailun Road Shanghai 201203 P.R. China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ange.202111376

Reference109 articles.

2. Maraviroc (UK-427,857), a Potent, Orally Bioavailable, and Selective Small-Molecule Inhibitor of Chemokine Receptor CCR5 with Broad-Spectrum Anti-Human Immunodeficiency Virus Type 1 Activity

3. Aurora Kinase Inhibitors Based on the Imidazo[1,2-a]pyrazine Core: Fluorine and Deuterium Incorporation Improve Oral Absorption and Exposure

4. Metabolism, Excretion, and Pharmacokinetics of ((3,3-Difluoropyrrolidin-1-yl)((2S,4S)-4-(4-(pyrimidin-2-yl)piperazin-1-yl)pyrrolidin-2-yl)methanone, a Dipeptidyl Peptidase Inhibitor, in Rat, Dog and Human

5. Recent advances in functionalization ofgem-difluoroalkenes see reviews:

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2. Enantio‐, Diastereo‐ and Regioselective Synthesis of Chiral Cyclic and Acyclic gem ‐Difluoromethylenes by Palladium‐Catalyzed [4+2] Cycloaddition;Angewandte Chemie;2022-04-13