Reshaping the 2‐Pyrone Synthase Active Site for Chemoselective Biosynthesis of Polyketides

Author:

Zhou Yu12ORCID,Mirts Evan N.1,Yook Sangdo134,Waugh Matthew1,Martini Rachel5,Jin Yong‐Su134ORCID,Lu Yi12ORCID

Affiliation:

1. DOE Center for Advanced Bioenergy and Bioproducts Innovation University of Illinois at Urbana-Champaign 1206 W Gregory Dr Urbana IL 61801 USA

2. Department of Chemistry The University of Texas at Austin 105 E 24th St Austin TX 78712 USA

3. Department of Food Science and Human Nutrition University of Illinois at Urbana-Champaign 905 S. Goodwin Avenue Urbana IL 61801 USA

4. Carl R. Woese Institute for Genomic Biology University of Illinois at Urbana-Champaign 1206 W Gregory Dr Urbana IL 61801 USA

5. Department of Biochemistry University of Illinois at Urbana-Champaign 600 South Mathews Avenue Urbana IL 61801 USA

Funder

U.S. Department of Energy

Welch Foundation

Publisher

Wiley

Subject

General Medicine

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