Enzymatic Tailoring in Luzopeptin Biosynthesis Involves Cytochrome P450‐Mediated Carbon–Nitrogen Bond Desaturation for Hydrazone Formation-Reference-Cited by-同舟云学术

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Enzymatic Tailoring in Luzopeptin Biosynthesis Involves Cytochrome P450‐Mediated Carbon–Nitrogen Bond Desaturation for Hydrazone Formation

Published:2021-08-03 Issue:36 Volume:133 Page:19974-19981
ISSN:0044-8249
Container-title:Angewandte Chemie
language:en
Short-container-title:Angew. Chem.

Author:

Shi Xinjie¹²,Huang Liming¹,Song Kaihui¹,Zhao Guiyun¹,Liu Yu³,Lv Longxian²,Du Yi‐Ling¹²^ORCID

Affiliation:

1. Institute of Pharmaceutical Biotechnology and The First Affiliated Hospital Zhejiang University School of Medicine 310058 Hangzhou China

2. State Key Laboratory for Diagnosis and Treatment of Infectious Diseases The First Affiliated Hospital Zhejiang University 310003 Hangzhou China

3. College of Life Sciences Zhejiang University 310058 Hangzhou China

Funder

Key Technologies Research and Development Program

Natural Science Foundation of Zhejiang Province

National Natural Science Foundation of China

Publisher

Wiley

Subject

General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ange.202105312

Reference37 articles.

1. Bisintercalator natural products with potential therapeutic applications: isolation, structure determination, synthetic and biological studies

2. Recent developments in bisintercalator natural products

3. Biosynthetic Modularity Rules in the Bisintercalator Family of Antitumor Compounds

4. Total Syntheses of Thiocoraline and BE-22179 and Assessment of Their DNA Binding and Biological Properties

5. Total Synthesis and Comparative Evaluation of Luzopeptin A−C and Quinoxapeptin A−C

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1. Identification of a novel cytochrome P450 17A2 enzyme catalyzing the C17α hydroxylation of progesterone and its application in engineered Pichia pastoris;Biochemical Engineering Journal;2022-01

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