Tuning an Imine Reductase for the Asymmetric Synthesis of Azacycloalkylamines by Concise Structure‐Guided Engineering-Reference-Cited by-同舟云学术

Tuning an Imine Reductase for the Asymmetric Synthesis of Azacycloalkylamines by Concise Structure‐Guided Engineering

Published:2022-04-07 Issue:24 Volume:134 Page:
ISSN:0044-8249
Container-title:Angewandte Chemie
language:en
Short-container-title:Angewandte Chemie

Author:

Zhang Jun¹²,Liao Daohong³,Chen Rongchang⁴,Zhu Fangfang⁵,Ma Yaqing¹,Gao Lei⁶,Qu Ge²,Cui Chengsen²,Sun Zhoutong²,Lei Xiaoguang⁶,Gao Shu‐Shan¹²^ORCID

Affiliation:

1. State Key Laboratory of Microbial Resources, Institute of Microbiology Chinese Academy of Sciences Beijing 100101 China

2. Tianjin Institute of Industrial Biotechnology Chinese Academy of Sciences Tianjin 300308 China

3. Jiangsu JITRI Molecular Engineering Inst. Co., Ltd. Jiangsu 215500 China

4. ReadCrystal Bio-tech Co. LTD Suzhou 215505 China

5. College of Biotechnology Tianjin University of Science & Techno Tianjin 300457 China

6. Beijing National Laboratory for Molecular Sciences Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Department of Chemical Biology College of Chemistry and Molecular Engineering Synthetic and Functional Biomolecules Center Peking-Tsinghua Center for Life Sciences Peking University Beijing 100091 China

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

Wiley

Subject

General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ange.202201908

Reference80 articles.

2. Application of ω-Transaminases in the Pharmaceutical Industry

3. Reductive Amination in the Synthesis of Pharmaceuticals

5. Transition-Metal-Catalyzed Asymmetric Couplings of α-Aminoalkyl Fragments to Access Chiral Alkylamines

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