Inverting the Enantiopreference of Nitrilase‐Catalyzed Desymmetric Hydrolysis of Prochiral Dinitriles by Reshaping the Binding Pocket with a Mirror‐Image Strategy-Reference-Cited by-同舟云学术

Inverting the Enantiopreference of Nitrilase‐Catalyzed Desymmetric Hydrolysis of Prochiral Dinitriles by Reshaping the Binding Pocket with a Mirror‐Image Strategy

Published:2020-12-14 Issue:7 Volume:133 Page:3723-3728
ISSN:0044-8249
Container-title:Angewandte Chemie
language:en
Short-container-title:Angew. Chem.

Author:

Yu Shanshan¹^ORCID,Li Jinlong¹^ORCID,Yao Peiyuan¹^ORCID,Feng Jinhui¹^ORCID,Cui Yunfeng¹^ORCID,Li Jianjiong¹^ORCID,Liu Xiangtao¹^ORCID,Wu Qiaqing¹^ORCID,Lin Jianping¹^ORCID,Zhu Dunming¹^ORCID

Affiliation:

1. National Technology Innovation Center of Synthetic Biology National Engineering Laboratory for Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology Tianjin Institute of Industrial Biotechnology Chinese Academy of Sciences 32 Xi Qi Dao, Tianjin Airport Economic Area Tianjin 300308 P. R. China

Funder

National Natural Science Foundation of China

Chinese Academy of Sciences

Natural Science Foundation of Tianjin Municipal Science and Technology Commission

Ministry of Science and Technology of the People's Republic of China

Publisher

Wiley

Subject

General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ange.202012243

Reference85 articles.

2. 3-Alkyl-4-aminobutyric acids: the first class of anticonvulsant agents that activates L-glutamic acid decarboxylase

3. Cell-Penetrating cis-γ-Amino-l-Proline-Derived Peptides

4. Stereoselective synthesis of γ-amino acids

5. An update on the stereoselective synthesis of γ-amino acids

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