Combined Afirma Genomic Sequencing Classifier and TERT promoter mutation detection in molecular assessment of Bethesda III–VI thyroid nodules

Author:

Ladenson Paul W.1,Klopper Joshua P.2,Hao Yangyang3,Kaushik Praveen4,Walsh P. Sean3,Huang Jing3,Kloos Richard T.2ORCID,Ali Syed Z.5

Affiliation:

1. Division of Endocrinology, Diabetes, and Metabolism Department of Medicine The Johns Hopkins University School of Medicine Baltimore Maryland USA

2. Department of Medical Affairs Veracyte South San Francisco California USA

3. Department of Research and Development Veracyte South San Francisco California USA

4. Department of Marketing Veracyte South San Francisco California USA

5. Department of Pathology The Johns Hopkins University School of Medicine Baltimore Maryland USA

Abstract

Molecular analysis of thyroid nodules can provide diagnostic and prognostic information as well as indicate opportunities for targeted therapy. Whole RNA exome analysis offers information that can be leveraged to predict tumor behavior.

Publisher

Wiley

Subject

Cancer Research,Oncology

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