Human interleukin-10 delivered intrathecally by self-complementary adeno-associated virus 8 induces xenogeneic transgene immunity without clinical neurotoxicity in swine-Reference-Cited by-同舟云学术

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Human interleukin-10 delivered intrathecally by self-complementary adeno-associated virus 8 induces xenogeneic transgene immunity without clinical neurotoxicity in swine

Published:2018-06-15 Issue:7-8 Volume:20 Page:e3026
ISSN:1099-498X
Container-title:The Journal of Gene Medicine
language:en
Short-container-title:J Gene Med

Author:

Unger Mark D.¹,Pleticha Josef¹,Heilmann Lukas F.¹,Newman Laura K.¹,Maus Timothy P.²,Beutler Andreas S.¹

Affiliation:

1. Departments of Anesthesiology and Oncology, Mayo Clinic, Translational Science Track, Mayo Graduate School; Rochester MN USA

2. Department of Radiology (Section of Interventional Pain Management), Mayo Clinic; Rochester MN USA

Funder

National Institute of Neurological Disorders and Stroke

Publisher

Wiley

Subject

Genetics (clinical),Drug Discovery,Genetics,Molecular Biology,Molecular Medicine

Reference29 articles.

1. The therapeutic potential of interleukin-10 in neuroimmune diseases;Kwilasz;Neuropharmacology,2015

2. Sensory neuron targeting by self-complementary AAV8 via lumbar puncture for chronic pain;Storek;Proc Natl Acad Sci U S A,2008

3. Intrathecal long-term gene expression by self-complementary adeno-associated virus type 1 suitable for chronic pain studies in rats;Storek;Mol Pain,2006

4. Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10;Milligan;Mol Pain,2005

5. Novel immunotherapeutic avenues for rheumatoid arthritis;Semerano;Trends Mol Med,2016

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