Dosing of Ceftriaxone and Metronidazole for Children With Severe Acute Malnutrition

Author:

Standing Joseph F.12,Ongas Martin O.34,Ogwang Caroline5,Kagwanja Nancy5,Murunga Sheila5,Mwaringa Shalton5,Ali Rehema5,Mturi Neema5,Timbwa Moline56,Manyasi Christine56,Mwalekwa Laura57,Bandika Victor L.7,Ogutu Bernhards34,Waichungo Joseph5,Kipper Karin89,Berkley James A.51011,

Affiliation:

1. Great Ormond Street Institute of Child Health; University College London; London UK

2. Paediatric Infectious Diseases Research Group; Institute for Infection and Immunity, St. George's, University of London; London UK

3. Center for Research in Therapeutic Sciences; Strathmore University; Nairobi Kenya

4. KEMRI-Centre for Clinical Research; Nairobi Kenya

5. KEMRI-Wellcome Trust Research Programme; Kilifi Kenya

6. Mbagathi County Hospital; Nairobi Kenya

7. Coast General Hospital; Mombasa Kenya

8. Analytical Services International, St George's University of London; London UK

9. Institute of Chemistry; University of Tartu; Tartu Estonia

10. The Childhood Acute Illness & Nutrition (CHAIN) Network; Nairobi Kenya

11. Centre for Tropical Medicine & Global Health, Nuffield Department of Medicine; University of Oxford; Oxford UK

Funder

United Kingdom Medical Research Council/Department for International Development/Wellcome Trust Joint Global Health Trials Scheme

United Kingdom Medical Research Council Fellowship

National Institute for Health Research

Hospital for Children NHS Foundation Trust

Bill & Melinda Gates Foundation

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference39 articles.

1. Inpatient management of children with severe acute malnutrition: a review of WHO guidelines;Tickell;Bull. World Health Organ,2016

2. Antibiotics in severely malnourished children: systematic review of efficacy, safety and pharmacokinetics;Lazzerini;Bull. World Health Organ,2011

3. severe acute malnutrition update: Current WHO guidelines and the WHO essential medicine list for children;Williams;J. Clin. Pharmacol,2016

4. Protein binding characteristics and pharmacokinetics of ceftriaxone in intensive care unit patients;Schleibinger;Br. J. Clin. Pharmacol,2015

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