DSP‐1053, a novel serotonin reuptake inhibitor with 5‐HT 1A partial agonistic activity, displays fast antidepressant effect with minimal undesirable effects in juvenile rats-Reference-Cited by-同舟云学术

DSP‐1053, a novel serotonin reuptake inhibitor with 5‐HT 1A partial agonistic activity, displays fast antidepressant effect with minimal undesirable effects in juvenile rats

Published:2015-05-08 Issue:3 Volume:3 Page:
ISSN:2052-1707
Container-title:Pharmacology Research & Perspectives
language:en
Short-container-title:Pharmacol Res Perspect

Author:

Kato Taro¹,Matsumoto Yuji²,Yamamoto Masanori²,Matsumoto Kenji¹,Baba Satoko¹,Nakamichi Keiko¹,Matsuda Harumi²,Nishimuta Haruka³,Yabuuchi Kazuki⁴

Affiliation:

1. Drug Development Research Laboratories Sumitomo Dainippon Pharma Co. Ltd. Osaka Japan

2. Innovative Drug Discovery Laboratories Sumitomo Dainippon Pharma Co. Ltd. Osaka Japan

3. Preclinical Research Laboratories Sumitomo Dainippon Pharma Co. Ltd. Osaka Japan

4. Project Management Sumitomo Dainippon Pharma Co. Ltd. Osaka Japan

Funder

Dainippon Sumitomo Pharma

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/prp2.142

Reference58 articles.

1. 5-HT1A receptor antagonists increase the activity of serotonergic cells in the dorsal raphe nucleus in rats treated acutely or chronically with citalopram

2. The 5-HT1A receptor antagonist (S)-UH-301 augments the increase in extracellular concentrations of 5-HT in the frontal cortex produced by both acute and chronic treatment with citalopram

3. Pindolol Induces a Rapid Improvement of Depressed Patients Treated With Serotonin Reuptake Inhibitors

4. Acceleration of the effect of selected antidepressant drugs in major depression by 5-HT1A antagonists

5. Chronic treatment with fluvoxamine increases extracellular serotonin in frontal cortex but not in raphe nuclei

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