Oncological and functional outcomes for transoral robotic surgery following previous radiation treatment for upper aerodigestive tract head and neck cancers. A French multicenter <scp>GETTEC</scp> group study-Reference-Cited by-同舟云学术

Oncological and functional outcomes for transoral robotic surgery following previous radiation treatment for upper aerodigestive tract head and neck cancers. A French multicenter GETTEC group study

Published:2024-03-28 Issue:7 Volume:13 Page:
ISSN:2045-7634
Container-title:Cancer Medicine
language:en
Short-container-title:Cancer Medicine

Author:

Malard Olivier¹^ORCID,Karakachoff Matilde²,Ferron Christophe¹,Hans Stéphane³,Vergez Sébastien⁴^ORCID,Garrel Renaud⁵,Gorphe Philippe⁶^ORCID,Ramin Lionel⁷,Santini Laure⁸,Villeneuve Alexandre⁹,Lasne‐Cardon Audrey¹⁰,Espitalier Florent¹,Hounkpatin Audrey¹

Affiliation:

1. Department of Otolaryngology Head and Neck Surgery Nantes University Hospital Nantes France

2. Nantes Université, CHU Nantes, Pôle Hospitalo‐Universitaire 11: Santé Publique, Clinique des données, INSERM, CIC 1413 Nantes France

3. Department of Otolaryngology‐Head and Neck Surgery Foch Hospital Suresnes France

4. Head and Neck Surgery Department Cancer Institute Toulouse‐Oncopole Toulouse France

5. Department of Head and Neck Surgery Montpellier Guy De Chauliac University Hospital Montpellier France

6. Department of Head and Neck Oncology, Gustave Roussy Institute University Paris‐Saclay Villejuif France

7. Department of Head and Neck Surgery Limoges Dupuytrens University Hospital Limoges France

8. ENT—Head and Neck Surgery Department, La Conception University Hospital Aix Marseille University Marseille France

9. Head and Neck Surgery Department, Georges‐Pompidou European Hospital Paris France

10. Department of Head and Neck Surgery, François Baclesse Cancer center Normandie University Caen France

Abstract

AbstractBackgroundTransoral robotic surgery (TORS) opens new perspectives. We evaluated the outcomes for patients having undergone TORS after previous radiotherapy.MethodsA retrospective multicenter study (n = 138) in a previously irradiated area between 2009 and 2020. Survival was assessed with the Kaplan–Meier method. Prognostic factors were evaluated using a chi‐squared test, Fisher's test, or Wilcoxon's test.ResultsThe median length of hospital stay was 12.5 days. Bleeding was the most frequent postoperative complication (15.2%, n = 22). Prophylactic vessel ligation did not significantly decrease bleeding. Complications were significantly lower for Tis, T1, and N0 tumors. 91.6% (n = 120) of the patients with a perioperative tracheotomy could be decannulated. Larynx was functional for 65.94% of the patients. The median length of follow‐up was 26 months. The 5‐year overall and relapse‐free survival rates were respectively 59.9% and 43.4%.ConclusionOncological and functional results confirmed the value of TORS as a treatment in previously irradiated area.

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cam4.7031

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