Cyclosporine in combination with mycophenolate mofetil versus methotrexate for graft versus host disease prevention in myeloablative HLA-identical sibling donor allogeneic hematopoietic cell transplantation

Author:

Hamilton Betty K.1,Rybicki Lisa2,Dean Robert1,Majhail Navneet S.1,Haddad Housam3,Abounader Donna1,Hanna Rabi4,Sobecks Ronald1,Duong Hien1,Hill Brian T.1,Copelan Edward5,Bolwell Brian1,Kalaycio Matt1

Affiliation:

1. Blood & Marrow Transplant Program; Department of Hematologic Oncology and Blood Disorders; Cleveland Clinic Taussig Cancer Institute; Cleveland Ohio

2. Quantitative Health Sciences; Cleveland Clinic Lerner Research Institute; Cleveland Ohio

3. Hematology/Oncology; Staten Island University Hospital; New York New York

4. Pediatric Hematology Oncology; Cleveland Clinic; Cleveland Ohio

5. Levine Cancer Institute; Carolinas HealthCare System; Charlotte North Carolina

Publisher

Wiley

Subject

Hematology

Reference42 articles.

1. Treatment of moderate/severe acute graft-versus-host disease after allogeneic bone marrow transplantation: An analysis of clinical risk features and outcome;Weisdorf;Blood,1990

2. Phase 3 study comparing methotrexate and tacrolimus with methotrexate and cyclosporine for prophylaxis of acute graft-versus-host disease after marrow transplantation from unrelated donors;Nash;Blood,2000

3. Phase III study comparing methotrexate and tacrolimus (prograf, FK506) with methotrexate and cyclosporine for graft-versus-host disease prophylaxis after HLA-identical sibling bone marrow transplantation;Ratanatharathorn;Blood,1998

4. Methotrexate and cyclosporine compared with cyclosporine alone for prophylaxis of acute graft versus host disease after marrow transplantation for leukemia;Storb;N Engl J Med,1986

5. Purine metabolism and immunosuppressive effects of mycophenolate mofetil (MMF);Allison;Clin Transplant,1996

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