Polycomb Group (PcG) Proteins and Human Cancers: Multifaceted Functions and Therapeutic Implications

Author:

Wang Wei12,Qin Jiang-Jiang1,Voruganti Sukesh1,Nag Subhasree1,Zhou Jianwei3,Zhang Ruiwen12

Affiliation:

1. Department of Pharmaceutical Sciences, School of Pharmacy; Texas Tech University Health Sciences Center; Amarillo TX 79106

2. Center for Cancer Biology and Therapy, School of Pharmacy; Texas Tech University Health Sciences Center; Amarillo TX 79106

3. Department of Molecular Cell Biology and Toxicology, Cancer Center, School of Public Health; Nanjing Medical University; Nanjing 210029 P. R. China

Funder

National Institutes of Health

Publisher

Wiley

Subject

Drug Discovery,Pharmacology,Molecular Medicine

Reference336 articles.

1. A gene complex controlling segmentation in Drosophila;Lewis;Nature,1978

2. A gene product required for correct initiation of segmental determination in Drosophila;Struhl;Nature,1981

3. Polycomblike: A gene that appears to be required for the normal expression of the bithorax and antennapedia gene complexes of Drosophila melanogaster;Duncan;Genetics,1982

4. In vivo binding pattern of a trans-regulator of homoeotic genes in Drosophila melanogaster;Zink;Nature,1989

5. Transcriptional repression by Drosophila and mammalian Polycomb group proteins in transfected mammalian cells;Bunker;Mol Cell Biol,1994

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