Amenamevir: Studies of Potential CYP3A-Mediated Pharmacokinetic Interactions With Midazolam, Cyclosporine, and Ritonavir in Healthy Volunteers

Author:

Adeloye Temitope1,Sahgal Omair1,Puri Adeep1,Warrington Steve1,Endo Takamasa2,Dennison Jeremy1,Johnston Atholl3

Affiliation:

1. Hammersmith Medicines Research; London England

2. Maruho Co Ltd; Kyoto Japan

3. Analytical Services International; St George's University of London; London England

Funder

Maruho

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science

Reference16 articles.

1. ASP2151, a novel helicase-primase inhibitor, possesses antiviral activity against varicella-zoster virus and herpes simplex virus types 1 and 2;Chono;J Antimicrob Chemother,2010

2. Valaciclovir. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in herpesvirus infections;Perry;Drugs,1996

3. Resistance of herpes simplex virus infections to nucleoside analogues in HIV-infected patients;Levin;Clin Infect Dis,2004

4. The relative contributions of CYP3A4 and CYP3A5 to the metabolism of vinorelbine;Topletz;Drug Metab Dispos,2013

5. Food and Drug Administration Center for Drug Evaluation and Research (CDER) Guidance for Industry: Drug Interaction Studies-Study Design, Data Analysis, Implications for Dosing, and Labeling Recommendations 2012 46 47

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