RecurrentMYOD1mutations in pediatric and adult sclerosing and spindle cell rhabdomyosarcomas: Evidence for a common pathogenesis

Author:

Agaram Narasimhan P.1,Chen Chun-Liang1,Zhang Lei1,LaQuaglia Michael P.2,Wexler Leonard3,Antonescu Cristina R.1

Affiliation:

1. Department of Pathology; Memorial Sloan Kettering Cancer Center; New York NY

2. Department of Pediatric Surgery; Memorial Sloan Kettering Cancer Center; New York NY

3. Department of Pediatrics; Memorial Sloan Kettering Cancer Center; New York NY

Funder

NIH

Publisher

Wiley

Subject

Cancer Research,Genetics

Reference22 articles.

1. Rhabdomyosarcomas do not contain mutations in the DNA binding domains of myogenic transcription factors;Anand;J Clin Invest,1994

2. Association of KIT exon 9 mutations with nongastric primary site and aggressive behavior: KIT mutation analysis and clinical correlates of 120 gastrointestinal stromal tumors;Antonescu;Clin Cancer Res,2003

3. SNP genotyping of a sclerosing rhabdomyosarcoma: Reveals highly aneuploid profile and a specific MDM2/HMGA2 amplification;Bouron-Dal Soglio;Hum Pathol,2009

4. Spindle cell rhabdomyosarcoma. A prognostically favorable variant of rhabdomyosarcoma;Cavazzana;Am J Surg Pathol,1992

5. Sclerosing rhabdomyosarcomas in children and adolescents: A clinicopathologic review of 13 cases from the Intergroup Rhabdomyosarcoma Study Group and Children's Oncology Group;Chiles;Pediatr Dev Pathol,2004

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