Ultra scale-down characterization of the impact of conditioning methods for harvested cell broths on clarification by continuous centrifugation-Recovery of domain antibodies from recE. coli-Reference-Cited by-同舟云学术

Ultra scale-down characterization of the impact of conditioning methods for harvested cell broths on clarification by continuous centrifugation-Recovery of domain antibodies from recE. coli

Published:2013-12-28 Issue:5 Volume:111 Page:913-924
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotechnol. Bioeng.

Author:

Chatel Alex¹,Kumpalume Peter²,Hoare Mike¹

Affiliation:

1. Department of Biochemical Engineering; UCL; Torrington Place, London WC1E 7JE UK

2. Biopharm Process Research; GlaxoSmithKline R&D; Stevenage UK

Funder

Engineering and Physical Sciences Research Council

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Reference43 articles.

1. The theory of scaling up laboratory data for the sedimentation type centrifuge;Ambler;J Biochem Microbiol Technol Eng,1959

2. Production technologies for monoclonal antibodies and their fragments;Andersen;Curr Opin Biotechnol,2004

3. Improving permeate flux and product transmission in the microfiltration of a bacterial cell suspension by flocculation with cationic polyelectrolytes;Aspelund;J Membr Sci,2008

4. Crossflow microfiltration of recombinant Escherichia coli lysates after high pressure homogenization;Bailey;Biotechnol Bioeng,1997

5. Growth and buoyant density of Escherichia coli at very low osmolarities;Baldwin;J Bacteriol,1995

Cited by 18 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Genomic DNA causes membrane fouling during sterile filtration of cell lysates;Separation and Purification Technology;2023-11

2. Integrated ultra scale-down and multivariate analysis of flocculation and centrifugation for enhanced primary recovery;Food and Bioproducts Processing;2023-05

3. Lipid reduction to improve clarification and filterability during primary recovery of intracellular products in yeast lysates using exogenous lipase;Journal of Chemical Technology & Biotechnology;2021-08-14

4. Reactor design for continuous monoclonal antibody precipitation based upon micro‐mixing;Journal of Chemical Technology & Biotechnology;2021-01-05

5. Microbial technologies for biotherapeutics production: Key tools for advanced biopharmaceutical process development and control;Drug Discovery Today: Technologies;2020-12