Affiliation:
1. Department of Endocrinology Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School Nanjing China
2. Xijing Hospital of PLA Air Force Medical University Xi'an China
3. Department of Endocrinology West China Hospital of Sichuan University Chengdu China
4. Department of Endocrinology The First Affiliated Hospital of Harbin Medical University Harbin China
5. Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science & Technology Wuhan China
6. Tangshan Gongren Hospital TangShan China
7. Department of Endocrinology The First Hospital of Shanxi Medical University Taiyuan China
8. Gansu Provincial Hospital Lanzhou China
9. Department of Endocrinology and Metabolism Nanfang Hospital Southern Medical University Guangzhou China
10. Department of Endocrinology Shanghai East Hospital Tongji University Shanghai China
11. Department of Endocrinology Xiangya Hospital of Central South University Changsha China
Abstract
AbstractAimsTo assess the prevalence of diabetic peripheral neuropathy (DPN) and its risk factors in the type 2 diabetes mellitus (T2DM) population.MethodsThis cross‐sectional study enroled patients with T2DM between July and December 2017 from 24 provinces in China. Diabetic peripheral neuropathy and its severity were assessed by the Toronto clinical scoring system, neuropathy symptoms score (NSS) and neuropathy disability score. The prevalence of DPN and its risk factors were analysed.ResultsA total of 14,908 patients with T2DM were enroled. The prevalence of DPN was 67.6%. Among 10,084 patients with DPN, 4808 (47.7%), 3325 (33.0%), and 1951 (19.3%) had mild, moderate, and severe DPN, respectively. The prevalence of DPN in females was higher than in males (69.0% vs. 66.6%, P = 0.002). The prevalence of DPN increased with age and course of diabetes and decreased with body mass index (BMI) and education level (all P for trend <0.05). The comorbidities and complications in patients with DPN were higher than in those without DPN, including hypertension, myocardial infarction, diabetic retinopathy, and diabetic nephropathy (all P < 0.001). Age, hypertension, duration of diabetes, diabetic retinopathy, diabetic nephropathy, glycated haemoglobin, high‐density lipoprotein cholesterol, and lower estimated glomerular filtration rate were positively associated with DPN, while BMI, education level, fasting C‐peptide, and uric acid were negatively associated with DPN.ConclusionsAmong patients with T2DM in China, the prevalence of DPN is high, especially in the elderly, low‐income, and undereducated patients.
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine
Cited by
2 articles.
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