Beyond cholesterol metabolism: The pleiotropic effects of proprotein convertase subtilisin/kexin type 9 (PCSK9). Genetics, mutations, expression, and perspective for long‐term inhibition-Reference-Cited by-同舟云学术

Beyond cholesterol metabolism: The pleiotropic effects of proprotein convertase subtilisin/kexin type 9 (PCSK9). Genetics, mutations, expression, and perspective for long‐term inhibition

Published:2020-01-30 Issue:3 Volume:46 Page:367-380
ISSN:0951-6433
Container-title:BioFactors
language:en
Short-container-title:BioFactors

Author:

Cesaro Arturo¹²^ORCID,Bianconi Vanessa³,Gragnano Felice¹²,Moscarella Elisabetta¹²,Fimiani Fabio¹²,Monda Emanuele²⁴,Scudiero Olga⁵⁶,Limongelli Giuseppe²⁴,Pirro Matteo³^ORCID,Calabrò Paolo¹²

Affiliation:

1. Division of Clinical CardiologyA.O.R.N. “Sant'Anna e San Sebastiano” Caserta Italy

2. Department of Translational Medical SciencesUniversity of Campania "Luigi Vanvitelli" Naples Italy

3. Unit of Internal Medicine, Department of MedicineUniversity of Perugia Perugia Italy

4. Division of CardiologyMonaldi Hospital Naples Italy

5. Dipartimento di Medicina Molecolare e Biotecnologie MedicheUniversità degli Studi di Naples “Federico II” Naples Italy

6. CEINGE‐Biotecnologie Avanzate Napoli Italy

Publisher

Wiley

Subject

Clinical Biochemistry,Molecular Medicine,General Medicine,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/biof.1619

Reference145 articles.

1. The unique role of proprotein convertase subtilisin/kexin 9 in cholesterol homeostasis

2. Proprotein Convertases Subtilisin/Kexin Type 9, an enzyme turned escort protein: Hepatic and extra hepatic functions (第9型前蛋白转换酶-枯草溶菌素/蛋白酶K，一种酶转变的护送蛋白：在肝脏与肝外的功能)

3. Mutations in PCSK9 cause autosomal dominant hypercholesterolemia

4. Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: Consensus Statement of the European Atherosclerosis Society

5. Lomitapide in homozygous familial hypercholesterolemia

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