Optimization of Bipyridinyl Pyrazole Scaffolds via Design, Synthesis and Screening of a New Series of ROS1 Kinase-modulating Compounds-Reference-Cited by-同舟云学术

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Optimization of Bipyridinyl Pyrazole Scaffolds via Design, Synthesis and Screening of a New Series of ROS1 Kinase-modulating Compounds

Published:2015-01 Issue:1 Volume:36 Page:305-311
ISSN:1229-5949
Container-title:Bulletin of the Korean Chemical Society
language:en
Short-container-title:Bull. Korean Chem. Soc

Author:

Al-Sanea Mohammad M.¹²,Park Byung Sun³,Abdelazem Ahmed Z.¹²,Selim Khalid B.⁴,Yoo Kyung Ho²,Sim Taebo²,Tae Jin Sung³,Lee So Ha²

Affiliation:

1. Department of Biological Chemistry; Korea University of Science and Technology; Daejeon 305-333 Republic of Korea

2. Chemical Kinomics Research Center; Korea Institute of Science and Technology; Seoul 136-791 Republic of Korea

3. Department of Chemistry; Yonsei University; Seoul 120-749 Republic of Korea

4. Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy; Mansoura University; Mansoura 35516 Egypt

Funder

National Research Foundation of Korea

Publisher

Wiley

Subject

General Chemistry

Reference24 articles.

1. Protein tyrosine kinase signaling diversity and susceptibility to targeted kinase inhibitors

2. Signal transduction therapy in haematological malignancies: identification and targeting of tyrosine kinases

3. Cell signalling: growth factors and tyrosine kinase receptors

4. Receptor tyrosine kinases: mechanisms of activation and signaling

5. Receptor tyrosine kinase mutations in myeloid neoplasms

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