13-valent pneumococcal conjugate vaccine (PCV13) is immunogenic and safe in children 6-17 years of age with sickle cell disease previously vaccinated with 23-valent pneumococcal polysaccharide vaccine (PPSV23): Results of a phase 3 study

Author:

De Montalembert Mariane1,Abboud Miguel R.2,Fiquet Anne3,Inati Adlette4,Lebensburger Jeffrey D.5,Kaddah Normeen6,Mokhtar Galila7,Piga Antonio8,Halasa Natasha9,Inusa Baba10,Rees David C.11,Heath Paul T.12,Telfer Paul13,Driscoll Catherine14,Al Hajjar Sami15,Tozzi Alberto16,Jiang Qin17,Emini Emilio A.18,Gruber William C.18,Gurtman Alejandra18,Scott Daniel A.18

Affiliation:

1. Hôpital Necker-Enfants Malades; Service de Pédiatrie; Paris France

2. Department of Pediatrics and Adolescent Medicine; American University of Beirut; Beirut Lebanon

3. Vaccine Research; Pfizer Ltd; Tadworth Berkshire UK

4. RHUH; Rafic Hariri University Hospital; Beirut Lebanon

5. University of Alabama at Birmingham; Birmingham; Alabama

6. Pediatric Cairo University Hospital (Abu Elreesh - Almoneera); Egypt

7. Hematology unit; Children Hospital; Ain Shams University; Cairo Egypt

8. Ospedale San Luigi Gonzaga; Orbassano; Torino University; Italy

9. Vanderbilt University Medical Center; Nashville Tennessee

10. Evelina Children's Hospital; St Thomas' Hospital; London UK

11. King's College Hospital; London UK

12. Vaccine Institute; St Georges; University of London; London UK

13. Royal London Hospital; London; UK

14. Children's Hospital at Montefiore; Bronx New York

15. King Faisal Specialist Hospital and Research Centre; Riyadh; Saudi Arabia

16. Unità Operativa di Epidemiologia Ospedale Bambino Gesù; Roma; Italy

17. Vaccines; Pfizer Inc; Collegeville Pennsylvania

18. Vaccine Research; Pfizer Inc; Pearl River New York

Funder

Pfizer Inc

Publisher

Wiley

Subject

Oncology,Hematology,Pediatrics, Perinatology and Child Health

Reference26 articles.

1. Sickle cell anemia and severe infections due to encapsulated bacteria;Pearson;J Infect Dis,1977

2. Mortality in children and adolescents with sickle cell disease. Cooperative Study of Sickle Cell Disease;Leikin;Pediatrics,1989

3. The Prophylactic Penicillin Study Group. Prophylaxis with oral penicillin in children with sickle cell anemia. A randomized trial;Gaston;N Engl J Med,1986

4. Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease;Hirst;Cochrane Database Syst Rev,2012

5. Trends in pediatric sickle cell disease-related mortality in the United States, 1983-2002;Yanni;J Pediatr,2009

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