Insulin-like growth factor-II is produced by, signals to and is an important survival factor for the mature podocyte in man and mouse

Author:

Hale LJ1,Welsh GI1,Perks CM2,Hurcombe JA1,Moore S3,Hers I3,Saleem MA1,Mathieson PW1,Murphy AJ4,Jeansson M4,Holly JM2,Hardouin SN5,Coward RJ1

Affiliation:

1. Academic and Children's Renal Unit, University of Bristol, Learning and Research; Southmead Hospital; Bristol BS10 5NB UK

2. IGFs and Metabolic Endocrinology Department, University of Bristol, Learning and Research; Southmead Hospital; Bristol BS10 5NB UK

3. Department of Physiology and Pharmacology, University of Bristol, Learning and Research; Southmead Hospital; Bristol BS10 5NB UK

4. Samuel Lunenfeld Research Institute, Mount Sinai Hospital; University of Toronto; Toronto Canada

5. INSERM UMR 967; Fontenay-aux-Roses F-92265 France

Publisher

Wiley

Subject

Pathology and Forensic Medicine

Reference54 articles.

1. Macroalbuminuria is a better risk marker than low estimated GFR to identify individuals at risk for accelerated GFR loss in population screening;Halbesma;J Am Soc Nephrol,2006

2. The relationship between proteinuria and coronary risk: a systematic review and meta-analysis;Perkovic;PLoS Med,2008

3. Cell biology of the glomerular podocyte;Pavenstadt;Physiol Rev,2003

4. The mesangial cell revisited: no cell is an island;Schlondorff;J Am Soc Nephrol,2009

5. Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis;Brown;Nat Genet,2009

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