Alterations in Wnt-β -catenin and Pten signalling play distinct roles in endometrial cancer initiation and progression

Author:

van der Zee Marten12,Jia Yundan12,Wang Yongyi12,Heijmans-Antonissen Claudia1,Ewing Patricia C2,Franken Patrick2,DeMayo Francesco J3,Lydon John P3,Burger Curt W1,Fodde Riccardo2,Blok Leen J1

Affiliation:

1. Department of Obstetrics and Gynaecology; Erasmus MC University Medical Centre; Rotterdam The Netherlands

2. Department of Pathology; Erasmus MC University Medical Centre; Rotterdam The Netherlands

3. Department of Molecular and Cellular Biology; Baylor College of Medicine; Houston TX USA

Publisher

Wiley

Subject

Pathology and Forensic Medicine

Reference39 articles.

1. APC, β-catenin, and E-cadherin and the development of recurrent endometrial carcinoma;Pijnenborg;Int J Gynecol Cancer,2004

2. Germline PTEN mutations as a cause of early-onset endometrial cancer;Blumenthal;J Clin Oncol,2008

3. p53 gene mutations in human endometrial carcinoma;Risinger;Mol Carcinog,1992

4. Abnormalities of the APC/β-catenin pathway in endometrial cancer;Moreno-Bueno;Oncogene,2002

5. Methylation of adenomatous polyposis coli in endometrial cancer occurs more frequently in tumors with microsatellite instability phenotype;Zysman;Cancer Res,2002

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