Angiopoietin-like protein 1 antagonizes MET receptor activity to repress sorafenib resistance and cancer stemness in hepatocellular carcinoma

Author:

Chen Hsin-An123,Kuo Tsang-Chih4,Tseng Chi-Feng56,Ma Jui-Ti5,Yang Shu-Ting5,Yen Chia-Jui7,Yang Ching-Yao8,Sung Shian-Ying9,Su Jen-Liang5101112

Affiliation:

1. Graduate Institute of Clinical Medicine, College of Medicine; Taipei Medical University; Taipei Taiwan

2. Division of General Surgery, Department of Surgery, Shuang Ho Hospital; Taipei Medical University; New Taipei City Taiwan

3. Division of General Surgery, Department of Surgery, School of Medicine, College of Medicine; Taipei Medical University; Taipei Taiwan

4. Institute of Biochemical Sciences, College of Life Science; National Taiwan University; Taipei Taiwan

5. National Institute of Cancer Research; National Health Research Institutes; Zhunan Taiwan

6. Graduate Program of Biotechnology in Medicine College of Life Science; National Tsing Hua University; Hsinchu Taiwan

7. Division of Hematology-Oncology, Department of Internal Medicine; National Cheng Kung University Hospital; Tainan Taiwan

8. Department of Surgery; National Taiwan University Hospital; Taipei Taiwan

9. Program for Translational Medicine, College of Medical Science and Technology; Taipei Medical University; Taipei Taiwan

10. Graduate Institute of Biomedical Sciences; China Medical University; Taichung Taiwan

11. Center for Molecular Medicine; China Medical University Hospital; Taichung Taiwan

12. Department of Biotechnology; Asia University; Taichung Taiwan

Funder

Ministry of Science and Technology (National Science Council)

National Health Research Institutes

Taipei Medical University-Shuang Ho Hospital, Ministry of Health and Welfare

Publisher

Wiley

Subject

Hepatology

Reference45 articles.

1. Cancer statistics, 2015;Siegel;CA Cancer J Clin,2015

2. The Barcelona approach: diagnosis, staging, and treatment of hepatocellular carcinoma;Llovet;Liver Transpl,2004

3. Management of hepatocellular carcinoma;Nakakura;Oncology (Williston Park),2000

4. Sorafenib in advanced hepatocellular carcinoma;Llovet;N Engl J Med,2008

5. Diagnosis and treatment of hepatocellular carcinoma;El-Serag;Gastroenterology,2008

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