Virus study for continuous low pH viral inactivation inside a coiled flow inverter

Author:

David Laura1ORCID,Maiser Benjamin2,Lobedann Martin1,Schwan Peter2,Lasse Michael3,Ruppach Horst3,Schembecker Gerhard4

Affiliation:

1. Invite GmbH, Biotech; Leverkusen Germany

2. Bayer AG, Engineering & Technology; Leverkusen Germany

3. Charles River Laboratories Germany GmbH, Biologics Testing Solutions; Cologne Germany

4. BCI, Plant and Process Design, Dortmund, TU Dortmund University; Germany

Funder

German federal ministry of education and research

European Union

The German Federal State North RhineWestphalia

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Reference22 articles.

1. ® ™ http://www.lgcstandards-atcc.org/products/all/CCL-64.aspx?geo_country=gb#generalinformation

2. ® ™ http://www.lgcstandards-atcc.org/products/all/CRL-2032.aspx?geo_country=gb#generalinformation

3. Rapid cell culture assay technique for murine leukaemia viruses;Bassin;Nature,1971

4. Identification of protein A media performance attributes that can be monitored as surrogates for retrovirus clearance during extended re-use;Brorson;Journal of Chromatography A,2003a

5. Bracketed generic inactivation of rodent retroviruses by low pH treatment for monoclonal antibodies and recombinant proteins;Brorson;Biotechnology and Bioengineering,2003b

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