Identification and validation of l ‐asparaginase as a potential metabolic target against Mycobacterium tuberculosis
Author:
Affiliation:
1. Kusuma School of Biological Sciences Indian Institute of Technology Delhi New Delhi India
Publisher
Wiley
Subject
Cell Biology,Molecular Biology,Biochemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcb.27169
Reference48 articles.
1. L-Asparaginase
2. Hyperthermophilic asparaginase mutants with enhanced substrate affinity and antineoplastic activity: structural insights on their mechanism of action
3. L-Asparaginase Therapy for Leukemia and Other Malignant Neoplasms
4. Crystal structure of Escherichia coli L-asparaginase, an enzyme used in cancer therapy.
5. Mycobacterium tuberculosis Exploits Asparagine to Assimilate Nitrogen and Resist Acid Stress during Infection
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2. Nitrogen metabolism in mycobacteria: the key genes and targeted antimicrobials;Frontiers in Microbiology;2023-05-18
3. Antimicrobial‐resistant Neisseria gonorrhoeae can be targeted using inhibitors against evolutionary conserved l ‐asparaginase;Journal of Cellular Biochemistry;2022-05-08
4. Natural phytocompounds physalin D, withaferin a and withanone target L-asparaginase of Mycobacterium tuberculosis: a molecular dynamics study;Journal of Biomolecular Structure and Dynamics;2022-02-08
5. Bioprospecting of the agaricomycete Ganoderma australe GPC191 as novel source for l-asparaginase production;Scientific Reports;2021-03-18
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