Financial Toxicity of Long‐Term Survivors Who Underwent Pancreatoduodenectomy for Pancreatic Ductal Adenocarcinoma

Author:

Muaddi Hala1ORCID,Zironda Andrea1ORCID,Zhang Chi2ORCID,Day Courtney3,Starlinger Patrick P.1,Warner Susanne G.1,Smoot Rory L.1,Kendrick Michael L.1,Cleary Sean P.1,Truty Mark J.1,Thiels Cornelius A.1

Affiliation:

1. Hepatobiliary and Pancreas Surgery Division, Department of Surgery Mayo Clinic Rochester Minnesota USA

2. Department of Surgery Mayo Clinic Arizona Phoenix Arizona USA

3. Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery Mayo Clinic Rochester Minnesota USA

Abstract

ABSTRACTBackgroundPancreatoduodenectomy (PD) for pancreatic cancer has a profound impact on patients' lives. However, the long‐term financial implications are poorly understood.ObjectiveAssess the financial burden of long‐term survivors who underwent PD.MethodsPatients who underwent PD between January 2011 and June 2019 were identified. To evaluate the long‐term financial burden, patients surviving ≥ 3 years post‐resection were prospectively surveyed using the Comprehensive Score for financial Toxicity (COST‐FACIT) and a customized institutionally developed questionnaire. A logistic regression model predicting high financial toxicity was used to identify predictive factors.ResultsAmong 238 eligible patients, 137 (57.6%) responded. Responders had a median age of 66 (59–73) years, with 86.7% identifying as financial prosperous or comfortable. However, 33.3% experienced financial distress due to treatment costs, 27.3% demonstrated high financial toxicity on the COST‐FACIT survey, and 37.2% made sacrifices to afford treatment. Only 8.9% stated that the treatment costs influenced their decisions, and the majority (85.9%) did not discuss financial implications with healthcare providers. Multivariable analysis identified younger age as a risk factor for high financial toxicity.ConclusionOne in three long‐term survivors experienced high financial toxicity, with younger age being a predictor. This emphasizes the need for efforts to provide comprehensive support and guidance to patients to navigate their oncological journey.

Publisher

Wiley

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