Exometabolome profiling reveals activation of the carnitine buffering pathway in fed‐batch cultures of CHO cells co‐fed with glucose and lactic acid
Author:
Affiliation:
1. Cellzome GmbH GlaxoSmithKline Heidelberg Germany
2. Microbial & Cell Culture Development GlaxoSmithKline King of Prussia Pennsylvania USA
Publisher
Wiley
Subject
Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/btpr.3198
Reference31 articles.
1. Bistability in Glycolysis Pathway as a Physiological Switch in Energy Metabolism
2. Significance ofl-carnitine for human health
3. Overview of coenzyme A metabolism and its role in cellular toxicity
4. Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
5. Multivariate analysis of cell culture bioprocess data—Lactate consumption as process indicator
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