Interconversion Rates between Conformational States as Rationale for the Membrane Permeability of Cyclosporines-Reference-Cited by-同舟云学术

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Interconversion Rates between Conformational States as Rationale for the Membrane Permeability of Cyclosporines

Published:2017-11-02 Issue:23 Volume:18 Page:3309-3314
ISSN:1439-4235
Container-title:ChemPhysChem
language:en
Short-container-title:ChemPhysChem

Author:

Witek Jagna¹,Mühlbauer Max¹,Keller Bettina G.²,Blatter Markus³,Meissner Axel³,Wagner Trixie³,Riniker Sereina¹^ORCID

Affiliation:

1. Laboratory of Physical Chemistry; ETH Zürich; Vladimir-Prelog-Weg 2 8093 Zürich Switzerland

2. Department of Biology, Chemistry, Pharmacy; Freie Universität Berlin; Takustrasse 3 14195 Berlin Germany

3. Novartis Institutes for BioMedical Research; Novartis Pharma AG; Novartis Campus 4056 Basel Switzerland

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Eidgenössische Technische Hochschule Zürich

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

Physical and Theoretical Chemistry,Atomic and Molecular Physics, and Optics

Reference50 articles.

1. The exploration of macrocycles for drug discovery — an underexploited structural class

2. Peptide and peptoid foldamers in medicinal chemistry

3. Macrocycles Are Great Cycles: Applications, Opportunities, and Challenges of Synthetic Macrocycles in Drug Discovery

4. Macrocycles in new drug discovery

Cited by 52 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Taming Conformational Heterogeneity on Ion Racetrack to Unveil Principles that Drive Membrane Permeation of Cyclosporines;JACS Au;2024-03-16

2. Conformations of Macrocyclic Peptides Sampled by Nuclear Magnetic Resonance: Models for Cell-Permeability;Journal of the American Chemical Society;2023-12-08

3. Backbone N-methylation of peptides: Advances in synthesis and applications in pharmaceutical drug development;Bioorganic Chemistry;2023-12

4. Controlling the Chameleonic Behavior and Membrane Permeability of Cyclosporine Derivatives via Backbone and Side Chain Modifications;Journal of Medicinal Chemistry;2023-09-18

5. Lessons for Oral Bioavailability: How Conformationally Flexible Cyclic Peptides Enter and Cross Lipid Membranes;Journal of Medicinal Chemistry;2023-02-10

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