Role of Sinonasal Anatomic Variants in Recurrent Acute Rhinosinusitis

Author:

Sunyecz Ian1,Hunt Connor2,Ramadan Hassan H.1ORCID,Makary Chadi A.1ORCID

Affiliation:

1. Department of Otolaryngology Head and Neck Surgery West Virginia University Morgantown West Virginia U.S.A.

2. School of Medicine West Virginia University Morgantown West Virginia U.S.A.

Abstract

ObjectivesPrior studies evaluating the role of sinonasal anatomic variants with recurrent acute rhinosinusitis (RARS) are limited by inconsistent results. The goal of this study is to evaluate the association between sinonasal anatomic variants and RARS.MethodsA 1:2 retrospective case–control study was conducted using patients presenting to the rhinology clinic from August 2020 to January 2023. A total of 60 patients with RARS were compared to 120 control patients. RARS was diagnosed based on the International Consensus Statement on Allergy and Rhinology criteria of four or more independent episodes of acute rhinosinusitis per year with at least one episode documented by objective findings, with complete resolution of the infection in‐between episodes. Sinonasal anatomic variants included nasal septal deviation (NSD), concha bullosa (CB), infraorbital (Haller) cells, nasal septal spur in the middle meatus, and frontal sinus cells (supra‐agger, supra‐agger frontal, and suprabullar frontal cells).ResultsAge was similar in RARS and control patients (47.4 ± 16.5 vs. 49.3 ± 14.5, p = 0.432). Both the RARS group and control group were more likely to be female (78.3% vs. 77.5%, p = 0.899). There was no significant association between NSD and RARS compared to the control group (OR = 0.97, p = 0.916), and no significant association between any of the anatomic variants and RARS [infraorbital cells (OR = 0.64, p = 0.167), CB (OR = 0.84, p = 0.596), spur in the middle meatus (OR = 1.28, p = 0.514), supra‐agger (OR = 0.88, p = 0.708), supra‐agger frontal cells (OR = 0.97, p = 0.939), or suprabullar frontal cells (OR = 1.13, p = 0.766)].ConclusionOur findings suggest no association between nasal septal deviation or any of the anatomic variants studied and RARS.Level of Evidence3 Laryngoscope, 134:3489–3492, 2024

Publisher

Wiley

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