An Unusual Case of an <scp>ALK‐Negative</scp> Epithelioid Fibrous Histiocytoma in the External Auditory Canal-Reference-Cited by-同舟云学术

An Unusual Case of an ALK‐Negative Epithelioid Fibrous Histiocytoma in the External Auditory Canal

Published:2024-01-24 Issue: Volume: Page:
ISSN:0023-852X
Container-title:The Laryngoscope
language:en
Short-container-title:The Laryngoscope

Author:

Leff Morgan¹^ORCID,Quimby Alexandra²³^ORCID,Morgan Eric⁴,Brant Jason A.²⁵^ORCID

Affiliation:

1. Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania U.S.A.

2. Department of Otolaryngology—Head & Neck Surgery Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania U.S.A.

3. Department of Otolaryngology and Communication Science Upstate Medical University Syracuse New York U.S.A.

4. Department of Pathology and Laboratory Medicine Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania U.S.A.

5. Corporal Michael J. Crescenz Department of Veterans Affairs Medical Center Philadelphia Pennsylvania U.S.A.

Abstract

This article represents the first reported case in the external auditory canal of epithelioid fibrous histiocytoma (EFH), a rare benign cutaneous epithelioid neoplasm. Immunostaining revealed uncommon negative staining for anaplastic lymphoma kinase (ALK) expression. This case and literature review outline the diagnostic strategy for this highly unusual neoplasm. Laryngoscope, 2024

Publisher

Wiley

Subject

Otorhinolaryngology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/lary.31302

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