Vocal Fold Paralysis After Spinal and Epidural Anesthesia: A Case Report and Scoping Review

Author:

Contu Nicolò123,Gallus Roberto3ORCID,Profice Paolo24,Lucchetti Dario1,Degni Emilia5,Rizzo Davide56,Artuso Alberto3,Bussu Francesco56

Affiliation:

1. Physical Medicine and Rehabilitation Mater Olbia Hospital Olbia Italy

2. Institute of Neurology Mater Olbia Hospital Olbia Italy

3. Otolaryngology Mater Olbia Hospital Olbia Italy

4. UOC Neurologia—Dipartimento Scienze dell'invecchiamento, Neurologiche, Ortopediche e della Testa‐Collo Fondazione Policlinico Universitario A. Gemelli IRCCS Rome Italy

5. Otolaryngology Division Azienda Ospedaliero Universitaria Sassari Italy

6. Department of Medicine, Surgery and Pharmacy University of Sassari Sassari Italy

Abstract

ObjectivesCranial nerve paralysis is a rare complication of spinal and epidural anesthesia, and some cases of vocal fold paralysis (VFP) have been reported. The aim of this article is to report a case, identify evidence supporting the possibility of VFP being a complication of spinal and epidural anesthesia and to investigate the frequency, the characteristics, and the possible mechanisms of such a complication.Data SourcesCINAHL Complete, Google Scholar, Cochrane Library, Pubmed, and EMBASE.MethodsCase report according to CARE guidelines; scoping review according to PRISMA‐ScR criteria. All types of studies that reported on patients of any age and sex, all types of spinal/epidural anesthesia regardless of the location and of drugs used were included. A data extraction sheet was completed for each study selected for inclusion based on the full‐text screenings. Extracted data included: study characteristics, participant characteristics, intervention characteristics, outcome measures, clinical investigations. The study did not receive external funding.ResultsEight studies met inclusion criteria and a total of 13 events (in 12 patients, including ours) were reported to date. Although there are some hypotheses in regard to the mechanism underlying the phenomena, including mechanical and inflammatory ones, the exact cause is still unclear.ConclusionsOnly few cases of VFP after spinal or epidural anesthesia have been reported to date; however, it seems possible that VFP might be a potential underreported complication of such procedures. We believe that more research on the topic is warranted, especially considering the wide population potentially at risk.Level of EvidenceNA Laryngoscope, 2024

Publisher

Wiley

Subject

Otorhinolaryngology

Reference15 articles.

1. Single institutional analysis of trends over 45 years in etiology of vocal fold paralysis

2. Vocal Fold Immobility: A Longitudinal Analysis of Etiology Over 20 Years

3. Framework Surgery for Treatment of Unilateral Vocal Fold Paralysis

4. Parálisis de cuerda vocal tras anestesia epidural por cesárea

5. The 3rd National Audit Project of The Royal College of Anesthesists. NAP3: Major Complications of Central Neuraxial Block in the United Kingdom. Accessed November 1 2022.https://www.nationalauditprojects.org.uk/NAP3_home.

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