Synthesis of novel flexible tamoxifen analogues to overcome CYP2D6 polymorphism and their biological evaluation on MCF‐7 cell line
Author:
Affiliation:
1. Department of Pharmaceutical Chemistry, Faculty of Pharmacy and BiotechnologyGerman University in Cairo Cairo Egypt
2. Institute of Zoology, Faculty of BiologyTechnische Universität Dresden Dresden Germany
Funder
Science Technology and Development Fund
Publisher
Wiley
Subject
Drug Discovery
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ddr.21637
Reference42 articles.
1. Selective Estrogen Receptor Modulators (SERMs): Effects on Multiple Organ Systems
2. Design and synthesis of novel tamoxifen analogues that avoid CYP2D6 metabolism
3. Large-Scale Screening and Identification of Novel Ebola Virus and Marburg Virus Entry Inhibitors
4. Exploring the Structure–Activity Relationship and Mechanism of a Chromene Scaffold (CXL Series) for Its Selective Antiproliferative Activity toward Multidrug-Resistant Cancer Cells
5. Anthracyclines and taxanes in the neo/adjuvant treatment of breast cancer: does the sequence matter?
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