Mouse pancreatic beta cells express MHC class II and stimulate CD4+T cells to proliferate
Author:
Affiliation:
1. St. Vincent's Institute; Immunology and Diabetes Laboratory; Fitzroy; Victoria Australia
2. Department of Medicine; St. Vincent's Hospital; The University of Melbourne; Fitzroy Victoria Australia
Funder
National Health and Medical Research Council of Australia (NHMRC)
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/eji.201445378/fullpdf
Reference59 articles.
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2. Pathogenic mechanisms in type 1 diabetes: the islet is both target and driver of disease;Graham;Rev. Diabet. Stud.,2012
3. The role of CD4+ and CD8+ T cells in the destruction of islet grafts by spontaneously diabetic mice;Wang;Proc. Natl. Acad. Sci. USA,1991
4. CD4 T cells and their antigens in the pathogenesis of autoimmune diabetes;Haskins;Curr. Opin. Immunol.,2011
5. Proinsulin specific, HLA-DQ8 and HLA-DQ8 transdimer restricted, CD4+ T cells infiltrate the islets in type 1 diabetes;Pathiraja;Diabetes,2015
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