IL‐12/15/18‐preactivated NK cells suppress GvHD in a mouse model of mismatched hematopoietic cell transplantation
Author:
Affiliation:
1. Department of Obstetrics and Gynaecology University of Cambridge School of Clinical Medicine, National Institute for Health Research (NIHR) Cambridge Biomedical Research Centre Cambridge UK
Funder
Wellcome Trust
Leukaemia and Lymphoma Research
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/eji.201445200
Reference22 articles.
1. Suppression of graft-versus-host disease and amplification of graft-versus-tumor effects by activated natural killer cells after allogeneic bone marrow transplantation.
2. Effectiveness of Donor Natural Killer Cell Alloreactivity in Mismatched Hematopoietic Transplants
3. Cytotoxicity of CD56bright NK Cells towards Autologous Activated CD4+ T Cells Is Mediated through NKG2D, LFA-1 and TRAIL and Dampened via CD94/NKG2A
4. Activated, But Not Resting, T Cells Can Be Recognized and Killed by Syngeneic NK Cells
5. NK cells mediate reduction of GVHD by inhibiting activated, alloreactive T cells while retaining GVT effects
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