In vitro polyclonal activation of conventional T cells with a CD28 superagonist protects mice from acute graft versus host disease
Author:
Affiliation:
1. Institute for Virology and Immunobiology; University of Würzburg; Würzburg Germany
Funder
Wilhelm Sander-Stiftung
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/eji.201445317/fullpdf
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4. The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality;Taylor;Blood,2002
5. CD4(+)CD25(+) immunoregulatory T Cells: new therapeutics for graft-versus-host disease;Cohen;J. Exp. Med.,2002
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1. Combinations of anti-GITR antibody and CD28 superagonist induce permanent allograft acceptance by generating type 1 regulatory T cells;Science Advances;2022-08-05
2. CD28 Superagonist D665-mediated activation of mouse regulatory T cells maintains their phenotype without loss of suppressive quality;Immunobiology;2021-11
3. Human-like Response of Pig T Cells to Superagonistic Anti-CD28 Monoclonal Antibodies;The Journal of Immunology;2021-10-08
4. During acute graft versus host disease CD28 deletion in donor CD8+, but not CD4+, T cells maintain antileukemia responses in mice;European Journal of Immunology;2018-11-14
5. Protection of Mice from Acute Graft-versus-Host Disease Requires CD28 Co-stimulation on Donor CD4+ Foxp3+ Regulatory T Cells;Frontiers in Immunology;2017-06-23
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