p70S6K1in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in mice-Reference-Cited by-同舟云学术

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p70S6K1in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in mice

Published:2015-11-19 Issue:1 Volume:46 Page:212-222
ISSN:0014-2980
Container-title:European Journal of Immunology
language:en
Short-container-title:Eur. J. Immunol.

Author:

Sasaki Carl Y.¹,Chen Gang¹,Munk Rachel¹,Eitan Erez²,Martindale Jennifer¹,Longo Dan L.¹,Ghosh Paritosh¹

Affiliation:

1. Laboratory of Genetics; Intramural Research Program; National Institute on Aging; National Institutes of Health; Baltimore MD USA

2. Laboratory of Neurosciences; Intramural Research Program; National Institute on Aging; National Institutes of Health; Baltimore MD USA

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/eji.201445422/fullpdf

Reference37 articles.

1. IL-17 and Th17 Cells;Korn;Annu. Rev. Immunol.,2009

2. Differentiation of effector CD4 T cell populations (*);Zhu;Annu. Rev. Immunol.,2010

3. Metabolic regulation of T lymphocytes;MacIver;Annu. Rev. Immunol.,2013

4. The mammalian target of rapamycin: linking T cell differentiation, function, and metabolism;Powell;Immunity,2010

5. mTOR, metabolism, and the regulation of T-cell differentiation and function;Waickman;Immunol. Rev.,2012

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2. p70 S6 kinase as a therapeutic target in cancers: More than just an mTOR effector;Cancer Letters;2022-06

3. The deacetylase SIRT2 contributes to autoimmune disease pathogenesis by modulating IL-17A and IL-2 transcription;Cellular & Molecular Immunology;2022-05-06

4. Modulation of glucose metabolism by 2-Deoxy-D-Glucose (2DG) promotes IL-17 producing human T cell subsets;2022-03-13

5. Metabolism Characteristics of Th17 and Regulatory T Cells in Autoimmune Diseases;Frontiers in Immunology;2022-02-25

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