Allele-sensitive mutant, Itkas, reveals that Itk kinase activity is required for Th1, Th2, Th17, andiNKT-cell cytokine production
Author:
Affiliation:
1. Center for Infection and Pathobiology; Department of Microbiology and Immunology; Cornell University; Ithaca NY USA
2. Keck School of Medicine of University of Southern California; Los Angeles CA USA
Funder
National Institute of Allergy and Infectious Diseases
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/eji.201445087/fullpdf
Reference46 articles.
1. T-cell signaling regulated by the Tec family kinase, Itk;Andreotti;Cold Spring Harb. Perspect. Biol.,2010
2. Tec family kinases in T lymphocytes: cross-regulation of cytokine production and T-cell fates;Gomez-Rodriguez;FEBS Lett.,2011
3. Tec family kinases: Itk signaling and the development of NKT alphabeta and gammadelta T cells;Qi;FEBS J.,2011
4. The Tec kinases Itk and Rlk regulate NKT-cell maturation, cytokine production, and survival;Felices;J. Immunol,2008
5. Tec kinase Itk in gammadelta T cells is pivotal for controlling IgE production in vivo;Felices;Proc. Natl. Acad. Sci. USA,2009
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